White and gray matter damage in primary progressive MS
نویسندگان
چکیده
منابع مشابه
Measuring Gray Matter and White Matter Damage in MS: Why This is Not Enough
INTRODUCTION Over the past years, progress in cerebral magnetic resonance imaging (MRI) technology has increased the possibilities to quantify MS-related tissue changes, starting from lesion assessment in the white matter (WM) to the quantification of microstructural changes of the whole brain (1). This was expected to give full insight into the causes of MS patients’ deficits but despite all a...
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Primary progressive aphasia is a clinical syndrome that encompasses three major phenotypes: non-fluent/agrammatic, semantic and logopenic. These clinical entities have been associated with characteristic patterns of focal grey matter atrophy in left posterior frontoinsular, anterior temporal and left temporoparietal regions, respectively. Recently, network-level dysfunction has been hypothesize...
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Multiple sclerosis is a CNS autoimmune disease configured by demyelination, inflammation, and degeneration of axons. This disease inflict great harms to patients. The most common problem is inability to control musculoskeletal system and decrease in mobility. These consequences could vary from patients to patients. About 10-15% of all MS patients develop primary progressive MS (PPMS). Despite t...
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ژورنال
عنوان ژورنال: Neurology
سال: 2015
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000002237